Hepatitis of unknown origin puts Latin America on edge – More regions – United States

Case of acute childhood hepatitis of unknown originappeared in the United Kingdom and already confirmed in a dozen countries, stand at 190, the European Center for Prevention and Control reported on Tuesday diseases (ECDC).

(Read: Scientists manage to repair damaged liver tissue faster than ever)

Investigations are underway in all countries that have confirmed casesbut at the moment the cause of this hepatitis is still unknown”, declared the director of this reference body for infections of the European Union (EU), Andrea Ammon, during a press conference.

(You are interested: there is no relationship between childhood hepatitis and food or vaccines, says WHO)

UK, where the alert was given last day 5, More than a hundred cases have been detected and forty correspond to ten countries of the European Union (EU) and the European Economic Area (EEA), including Spain, to which must be added those registered in the United States and Israel.

Investigations of these cases, which caused one death and around twenty liver transplants, point to a “link” with an infection caused by an adenovirus, while viral hepatitis types A, B, C, D and E.

The World Health Organization (WHO) expressed concern three days ago that an adenovirus, normally associated with mild respiratory conditions, could cause acute inflammation of the liver.

It is difficult to make a risk assessment with so many unknowns, but the impact is significant.

The ECDC, which will release a new analysis of the disease this Thursday, said it would continue to monitor cases and collaborate with health authorities in the respective countries.

So far, no link between the cases or any association with travel has been detected.s,” Ammon said of an illness whose symptoms include abdominal pain, diarrhea or vomiting.

During his appearance, which coincides with Vaccination Week in Europe, Ammon also reported on the latest news regarding the coronavirus pandemic on the continent, characterized by reduced contagion and mortality, while vaccination does not made no significant progress.

Alert in Japan

Japanese health authorities are investigating a potential case of the new acute childhood hepatitis of unknown origin which has already been detected in 13 other countries and which totals approximately 170 confirmed cases to date.

“We have been informed that a possible case has been detected after hospitalization,” Japanese government spokesman Hirokazu Matsuno said at his daily press conference on Tuesday.

Matsuno pointed out that Japan is among the countries investigating this hepatitis of unknown origin which is detected mainly in children under the age of 10, and that the country is analyzing the case “based on the standards of the World Organization. Health (WHO)”.

When tested for hepatitis A to E, adenovirus and covid, all results were negative.

The patient in question, about whom few details have been provided, is a minor aged 16 or under.

According to local media, the Ministry of Health was informed on 21 following a notification from the hospital to the local authorities.

According to the WHO, the age of those affected currently varies between one month and 16 years, in most cases they do not have a fever, and in none of them the normal viruses associated with these conditions have been detected (hepatitis A, B, C, D and E). The Japanese miner did not need a liver transplant, as has been the case with other patients.

The Japanese government spokesman said his government “will continue to monitor the situation in other countries and cooperate closely with the WHO on the development of cases of this childhood hepatitis.”

The first ten cases of the novel acute hepatitis under investigation were reported by the UK to the WHO on April 5, in previously healthy children under 10 years old.

Faced with this abnormal increase in cases, the organization has asked the health networks that have identified some and other countries to continue investigations and take preventive measures.

The WHO does not recommend taking restrictive measures on international travel, because for the moment it has not identified that they are linked to the proliferation of cases.

The United States is investigating the cases

At least six US states have reported confirmed or suspected cases of liver disorders serious and unexplained disease in children that has been detected in countries around the world.

Delaware officials have confirmed a case in a child, according to an emailed statement, adding to earlier reports from Alabama, North Carolina and Illinois.

health officials in the state of New York and Wisconsin said they are investigating reports of hepatitis which match a description released last week by the Centers for Disease Control and Prevention (CDC).

More than 190 cases of severe pediatric hepatitis, or inflammation of the liver, have been reported in children with no existing health conditions in a dozen countries, including the UK, Canada and Japan.

Worldwide, there are approximately 70 to 150 million cases of HCV infection, with a rate of 400,000 to 700,000 deaths per year. The virus primarily attacks the liver.

The disorder has been seen mostly in children under the age of 10 and has left some needing liver transplants.

Researchers are studying links to infection with adenoviruses, a family of pathogens that most often cause cold-like symptoms, as well as Covid-19.

Researchers are still compiling reports of the disease,
and it’s too early to say it’s causing the series of illnesses, Anthony Fauci, chief medical adviser to President Joe Biden and director of the National Institute of Allergy and Infectious Diseases, said in an interview.

“It’s still a mystery,” Fauci said. “It seems to be associated with adenovirus, but it’s not certain.”

Reports of suspected cases in the United States began surfacing last week after the CDC notified healthcare providers of nine serious cases of hepatitis with no known cause in previously healthy children between the ages of one and six. in Alabama.

What’s most unusual about all of this is that adenoviruses don’t usually cause severe hepatitis in children without underlying health conditions.

Laboratory tests determined that several children had adenovirus type 41, which most often causes pediatric acute gastroenteritis, sometimes called gastroenteritis, which can cause nausea, vomiting, diarrhea and sometimes symptoms more serious.

North Carolina identified cases in two more children last month, who have since recovered. Neither was found to be infected with the adenovirus, authorities said. Illinois said Monday it had identified three cases of severe pediatric hepatitis, one of which required a liver transplant.

Delaware health officials said Tuesday they have identified a case in a boy under the age of 5, who is currently hospitalized and receiving treatment.

Matching Description In New York State and Wisconsin, health officials are investigating several cases that appear to match the CDC’s description.

Several states that responded to questions by email said they had not yet identified any cases that met the criteria and said they were working closely with other health departments in the United States and monitoring for close to their local situations.

The Wisconsin Department of Health Services will issue an alert to encourage health systems to report suspected cases, according to an email.

Because cases appear in clusters, andThey are likely to be caused by a viral organism, according to Tina Tanpediatric infectious disease physician at Lurie Children’s Hospital in Chicago and a member of the Infectious Diseases Society of America, but experts still largely don’t know what the virus might be.

Although several of the children also tested positive for COVID-19, Tan said the hepatitis cases were unlikely to be caused by SARS-CoV-2. None of the cases were attributed to the family of viruses known to cause acute hepatitis.

Children are usually vaccinated against hepatitis A, while hepatitis B and C are less common in children due to the way the infections are acquired, often through sexual contact or sharing needles.

A silver lining of the pandemic, Tan said, is better and earlier communication from the CDC, which has instructed health centers to report any cases of pediatric hepatitis of unknown origin to state health departments and state health departments. performing adenovirus tests.

*With EFE and AFP information

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